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Updated: Oct 10, 2026

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
Published on: October 1, 2016
A ratiometric fluorescence sensor based on HFeO-modified NH2-MIL-101(Fe) and Ru-embedded for supersensitive and
Fengqin Yin1, Xudong He1, Xueting Liu1
1School of Health Science and Engineering, Shanghai Engineering Research Center of Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, 200093, PR China.
Abstract:
An enhanced ratiometric fluorescence sensor Ru@HFeO@NH2-MIL-101 (Fe) for the determination of arsenate was constructed by using HFeO-modified NH2-MIL-101 (Fe) as the response signal and Ru(bpy)32+ as the reference signal, which can be used for sensitive and visual detection of As(V). Because the HFeO nanoparticles were cleverly in-situ generated within the NH2-MIL-101(Fe) framework, the adsorption capacity of As(V) was enhanced 32% and further increased fluorescence ratio. The sensor exhibited a good linear relationship within As(V) concentration range 0.05-1 and 3-30 µM, with a detection limit (LOD) of 0.039 µM. The sensor also exhibited good selectivity and practical application performance, and can be utilized by a smartphone for visual detection of As(V). This provides an effective method for the sensitive detection of As(V) in complex environmental conditions.
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