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Updated: Oct 10, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Effects of a 10-week light-intensity stretching program on arterial stiffness in third-trimester pregnant women: a
Jeongok G Logan1, Jamie Crandell2, Elizabeth Williams3
1University of Virginia, School of Nursing, Dept. of Research, USA.
Objectives:
To determine whether a 10-week light-intensity stretching program reduces arterial stiffness and blood pressure (BP) compared with walking in pregnant women with obesity at risk for preeclampsia.
Study Design:
Between 27 and 37 weeks' gestation, pregnant women with obesity (Body Mass Index [BMI] ≥30 kg/m2; <24 weeks' gestation) were randomized to daily 30-minute stretching or moderate-intensity walking. Both groups received motivational coaching and adherence monitoring.
Main Outcome Measures:
Arterial stiffness, assessed by carotid-femoral pulse wave velocity (cf-PWV), and brachial BP were measured at 27, 32, and 37 weeks' gestation and analyzed using linear mixed-effects models adjusted for age, BMI, race/ethnicity, and trait anxiety.
Results:
Baseline characteristics were similar between groups (mean age = 31.9 ± 4.9 years; BMI = 36.7 ± 4.9 kg/m2). Fifty-three participants were allocated to stretching and 55 to walking. No significant between-group differences were observed. At 37 weeks, cf-PWV was 0.44 m/s lower in the stretching group (95% CI: -1.06 to 0.18; p = 0.16). Systolic and diastolic BP were 3.6 and 3.0 mmHg lower (95% CI: -7.7 to 0.58; p = 0.09 and 95% CI: -6.32 to 0.34; p = 0.08, respectively) in the stretching group.
Conclusions:
Light-intensity stretching produced non-significant reductions in arterial stiffness and BP compared with moderate-intensity walking in pregnant women with obesity. The study enrolled fewer participants than planned, while participant attrition and lower-than-anticipated intervention adherence may have limited the statistical power to detect between-group differences. A larger trial is needed to determine whether stretching produces clinically meaningful reductions in arterial stiffness, BP and preeclampsia incidence.