Antihypertensive Treatment Patterns and Factors Associated with Blood Pressure Control Across Türkiye: A Multicenter...

This study aimed to evaluate office blood pressure control, antihypertensive treatment patterns, and factors associated with uncontrolled office blood pressure among adults attending family health centers across Türkiye.

This multicenter cross-sectional study was conducted across the 7 geographical regions of Türkiye from February to December 2025. Adults aged ≥ 18 years with previous hypertension, antihypertensive treatment, and/or elevated office blood pressure at the study visit were included. Controlled office blood pressure was defined as <140/90 mm Hg for the primary analysis; achievement of <130/80 mmHg was assessed descriptively. Antihypertensive agents, drug classes, clinical characteristics, and laboratory parameters were recorded. Multiple binary logistic regression analysis identified factors independently associated with uncontrolled office blood pressure.

Among 1483 participants, median age was 63.0 years and 60.2% were female. Of 1456 participants with classifiable blood pressure, 902 (62.0%) had office blood pressure < 140/90 mm Hg. At the lower threshold, 438 of 1458 participants (30.0%) had office blood pressure < 130/80 mm Hg. Two-drug therapy was most common (38.7%), followed by monotherapy (27.1%) and 3-drug therapy (18.5%). Older age and higher body mass index were associated with greater odds of uncontrolled office blood pressure, whereas female sex was associated with lower odds; geographical region and antihypertensive treatment category were also independently associated with office blood pressure control.

Office blood pressure was <140/90 mm Hg in nearly two-thirds of participants, whereas 30.0% met the descriptive <130/80 mm Hg threshold. Combination therapy predominated, and office blood pressure control was associated with demographic, clinical, regional, and treatment-related factors.