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N,N-Dimethylacetamide Exposure-Induced Acute Liver Failure
WonYang Kang1,2, Eun Young Kim1, Byung-Soon Choi1
1Department of Research for Occupational Health, Institute of Occupation and Environment, Korea Workers' Compensation & Welfare Service, Incheon, Republic of Korea.
Abstract:
This study aimed to share the case caused by N,N-Dimethylacetamide (DMAC) exposure. We report a 30-year-old man who died from DMAC exposure-induced acute liver failure after working in the cutting and cleansing of hollow fiber membranes for 5 days. While he was exposed to low-level DMAC by inhalation as the measurement of periodic working environment monitoring, considering his working method, considerable DMAC exposure via dermal absorption was suspected. Therefore, short-term, short-latency DMAC exposure via dermal absorption can cause fatal acute liver failure owing to idiosyncratic reactions.
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