RNA and protein synthesis of dyskeratotic cells in morbus Darier. An autoradiographic study

RNA and protein synthesis of dyskeratotic cells in Darier's disease was studied by autoradiography after in vitro incubation with 3H-uridine, 3H-leucine and 3H-histidine. These three isotopes were incorporated in cells constituting the basis and wall of the lacuna, while they did not accumulate in isolated acantholytic and dyskeratotic cells in the lacuna, corps ronds and grains.