Related Experiment Video

Updated: Oct 14, 2026

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
09:44

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen

Published on: November 27, 2019

Effects of vitamin B1/B6/B12 complex on methotrexate-induced hepatorenal toxicity in a short-term acute rat model

Ayça Toprak-Semiz1, Esra Deniz2, Atilla Topçu2

  • 1Department of Medical Pharmacology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize, Türkiye. ayca.semiz@erdogan.edu.tr.

Naunyn-Schmiedeberg'S Archives of Pharmacology
|October 12, 2026
PubMed

Keywords:
Acute hepatorenal toxicityLipid peroxidationMethotrexateOxidative stressVitamin B complex

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