Related Experiment Video
Updated: Oct 16, 2026

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
Published on: November 25, 2025
Keeping the body in mind: Development of the Transdiagnostic Global Impression-Somatic Symptoms and Signs (TGI-3S)
Roger S McIntyre1,2, Agota Barabassy3, Zsofia Borbala Dombi4
1Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Background:
It is well-established that mental illness is associated with excess and premature mortality. Consequently, the assessment of physical health should be routine in the evaluation of persons living with mental disorders. Herein, we introduce the development of a global instrument to assess physical health status in persons with mental disorders.
Methods:
Following the development of the Transdiagnostic Global Impression-Psychopathology (TGI-P) scale, a novel scale of physical health status, the Transdiagnostic Global Impression-Somatic Symptoms and Signs (TGI-3S), was created using similar principles. Scale development followed a multistage process involving (1) item generation using deductive methods, (2) two content validations by an expert panel, and (3) two iterative usability-testing rounds with patients and caregivers. These rounds therefore assessed understandability and ease of use for wording, visual format, and emotional/cognitive load of the instrument. The psychometric validation is underway.
Results:
The TGI-3S was developed as a front-end screening tool resulting in a broad somatic burden map, rather than a diagnostic instrument. Throughout the development process, experts, patients, and caregivers evaluated the TGI-3S positively. In the final usability round, 96% found the aim of the scale clear, and 87% considered the instructions easy to follow. The scale demonstrated high-level usability, with 72% completing the TGI-3S in <5 minutes. Emotional and cognitive burden of completing the TGI-3S was rated as low, and item wording was well-understood.
Conclusions:
With psychometric validation underway, the TGI-3S offers an anamnesis-embedded, brief, yet comprehensive tool for facilitating the assessment of somatic health in patients with mental disorders.
Related Concept Videos
Assessment of the Gastrointestinal System II: Health Perception Pattern
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Assessment of the Gastrointestinal System I: Subjective Data
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems related to...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Serum Laboratory Studies, Stool Test, Breath Test
Generalized Anxiety Disorder
Three Developmental Domains
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...