Related Experiment Video
Updated: Oct 17, 2026

Formulation of Vitamin A Tracer Doses for Administration to Human Subjects using Retinol Isotope Dilution Technique
Published on: March 31, 2026
Advancing Global Health Initiative Through Pediatric Vitamin A Supplementation
Tenica K Watt1, Erica A Alessandrini2, Suzanna Fitzpatrick2
1School of Nursing, University of Maryland, Baltimore, MD, USA twatt001@umaryland.edu.
Abstract:
Background: Malnutrition, particularly vitamin A deficiency, affects approximately 49% of children aged 6-59 months in sub-Saharan Africa, increasing the risks of morbidity, mortality, poor growth, and preventable blindness. Tanzania has followed the World Health Organization's (WHO) guidelines for biannual vitamin A supplementation (VAS) since 2004, but rural access remains limited. A preliminary assessment at a rural Tanzanian day care showed only 29% VAS coverage, indicating a substantial gap in coverage. Objective: To improve nutritional health among children aged 6-59 months through a comprehensive VAS program at a local day care in Tanzania. Methods: An interdisciplinary team coordinated structural and workflow changes, secured the supplement through established partnerships, and administered it to all 21 eligible children per WHO protocols. Results: All 21 eligible children enrolled in the day care received their initial dose of VAS at implementation. VAS was sustained at 100% among 29 children, including the 21 original children and 8 newly enrolled. Conclusions: A structured, community-based supplementation program in rural Tanzania successfully addressed critical gaps in vitamin A access for children aged 6-59 months. Implications for Nursing: This quality improvement project demonstrates the feasibility of global health collaboration through strategic planning, stakeholder engagement, and context sensitivity to improve child health outcomes.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Preventive Healthcare Services
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...