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[Long lasting psychotropic effects after long-term treatment with a hemoderivative].
Fortschritte Der Medizin
|April 5, 1979
Summary
This study on arteriosclerosis patients found that Actihaemyl treatment improved memory and behavior. These cognitive and psychophysical improvements were maintained for 12 weeks after therapy concluded.
Area of Science:
- Neuroscience
- Gerontology
- Pharmacology
Background:
- Limited research exists on the long-term effects of psychotropic therapies on brain activity.
- Vasoactive and metabolic substances are used in long-term therapies, but their lasting impact is poorly documented.
Purpose of the Study:
- To investigate the duration of psychotropic effects after long-term therapy with vasoactive/metabolic substances.
- To evaluate the sustained impact of Actihaemyl on cognitive and behavioral functions in elderly patients with arteriosclerosis.
Main Methods:
- A six-week, double-blind trial involving 32 arteriosclerosis patients (average age 72).
- Treatment administered: Actihaemyl (10 ml i.v. twice weekly).
- Results analyzed using variance analysis and psychometric testing.
Main Results:
- Significant improvements were observed in memory functions, creative behavior, and general psychophysical, emotional, social, and clinical behavior.
- These improvements were largely maintained 12 weeks post-therapy.
- In many areas, the 12-week post-therapy status exceeded the immediate post-therapy status.
Conclusions:
- Actihaemyl demonstrates a significant and lasting positive effect on cognitive and behavioral functions in patients with arteriosclerosis.
- The study highlights the potential for sustained therapeutic benefits beyond the treatment period.
- Further research is warranted to elucidate the mechanisms behind this long-term efficacy.