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Updated: Oct 18, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

The COX2-PGE2-PKA axis suppresses antiviral immunity by inhibiting mtDNA-dependent STING activation

Pham Thuy Tien Vo1, Julien Cicero2, Zichen Wang3

  • 1Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.

Cell Reports
|October 16, 2026
PubMed

Keywords:
CP: immunologyEP4STING signalingantiviral innate immunitycyclooxygenase-2herpes simplex virus type 1mitochondrial DNAmitophagyprostaglandin E2protein kinase Atype I interferons

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