The All of Us dataset in scientific research: a bibliometric study of its utilization through 2024

This study presents a comprehensive bibliometric analysis of research publications utilizing the All of Us Research Program dataset to characterize publication trends, collaboration networks, key research topics, and compliance with All of Us publication and presentation policies through December 2024.

A total of 561 publication titles were collected from the All of Us Publications Directory. Titles were then searched across Web of Science (WoS), Scopus, and PubMed, with WoS (475 publications identified) selected as the primary source for analysis. Productivity metrics, including publication growth, journal distribution, author productivity, and word frequency, were analyzed using Biblioshiny. Co-authorship and keyword co-occurrence networks were visualized in VOSviewer to reveal collaboration structures and emerging research themes.

Among the 475 analyzed publications, 2,803 authors were identified across 211 journals. The annual number of All of Us publications increased by 82.45% from 2015 to 2024. Major research themes included epidemiology, chronic conditions, genomics, and health disparities, with dermatology emerging as a particularly active area. Network analysis revealed strong intra-institutional ties and some cross-institutional collaborations, primarily among R1 universities.

This bibliometric study demonstrates a rapid rise in scholarly activity leveraging the All of Us dataset, characterized by concentrated author and institutional engagement. These findings highlight both the growing impact of the All of Us dataset and opportunities to foster broader collaborations and diversify participation across the research community.