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Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)
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Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)

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Functional role of the second messengers PtdIns(3,4,5)P3 and PtdIns(3,4)P2 in carcinogenesis

Nina Nelson1,2, Manfred Jücker1

  • 1Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistraße 52, D-20246 Hamburg, Germany.

Biological Chemistry
|October 19, 2026
PubMed

Keywords:
2-PIP hypothesisPI3K/AKT/mTORC signalling pathwayPtdIns(3,4)P2PtdIns(3,4,5)P3cancerphosphoinositide detection techniques

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