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Updated: Oct 21, 2026
Application of an Amplitude-integrated EEG Monitor (Cerebral Function Monitor) to Neonates
Published on: September 6, 2017
Amplitude-integrated electroencephalogram (aEEG): A bedside window into newborn brain function in the NICU
Emily M Herzberg1, Mohamed El-Dib1
1Division of Newborn Medicine, Department of Pediatrics, Mass General Brigham for Children, 55 Fruit Street, Boston, MA, 02114, USA; Division of Newborn Medicine, Department of Pediatrics, Mass General Brigham for Children, 75 Francis Street, Boston, MA, 02115, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.
Abstract:
Amplitude-integrated electroencephalography (aEEG) remains an important tool for bedside neonatal brain monitoring. The rapid application of aEEG offers critical practical advantages for bedside clinicians assessing infants at risk for brain injury. aEEG has a distinct clinical niche in evaluations for hypoxic-ischemic encephalopathy (HIE) and as a first-line tool for seizure detection, alongside conventional video electroencephalogram (cEEG). Ultimately, the integration of aEEG with a broader multimodal neuromonitoring framework enhances neurodevelopmental prognostication and facilitates individualized bedside interventions, solidifying its relevance in contemporary neonatal neurocritical care.
