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Updated: Oct 22, 2026

Covalent Fragment Screening Using the Quantitative Irreversible Tethering Assay
06:17

Covalent Fragment Screening Using the Quantitative Irreversible Tethering Assay

Published on: February 28, 2025

In Pursuit of Enduring Inactivation: A Perspective on the Development and Study of Irreversible-Covalent Inhibitors

Matthias Gehringer1,2,3, David E Heppner4,5,6,7

  • 1Department of Medicinal Chemistry, Institute for Biomedical Engineering, Faculty of Medicine, Eberhard Karls Universität Tübingen, Tübingen72076, Germany.

Biochemistry
|October 20, 2026
PubMed

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