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Updated: Oct 22, 2026

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
Published on: May 26, 2021
BCL10 deficiency: Long-term immune reconstitution following hematopoietic stem cell transplantation
Marwa Ali1, Anas M Alazami2, Hamoud Al-Mousa1,3
1Section of Allergy and Immunology, Department of Pediatrics, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Abstract:
BCL10 deficiency is a rare combined immunodeficiency characterized by severe infections, chronic diarrhea, hypogammaglobulinemia, and impaired lymphocyte activation despite preserved lymphocyte counts. We report a novel homozygous BCL10 variant with durable cure and immune reconstitution following hematopoietic stem cell transplantation.
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