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Updated: Oct 22, 2026
DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
A dual-mode fluorescence sensing platform based on Zn2+@UiO-66-NH2 nanozyme for sensitive and wide-range detection of
Tong Xu1, Yuefei Luo1, Ruting Zheng1
1Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China. wang_min@cqu.edu.cn.
Abstract:
A dual-mode fluorescence platform based on a Zn2+@UiO-66-NH2 nanozyme is developed for ATP detection utilizing both the intrinsic fluorescence and phosphatase-like activity of the material. This strategy achieves a broad linear range (0.05-35 µM) and high sensitivity (with an LOD as low as 0.046 µM), offering a versatile tool for ATP analysis in biomedical research and pharmaceutical quality control.
