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Updated: Oct 22, 2026

Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms
13:40

Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms

Published on: July 7, 2011

Polycystin-2 functions as a calcium leak channel under endoplasmic reticulum stress to protect against myocardial

Virdjinija Vuchkovska1, Sanjeet Paluru2, Ryne M Knutila2

  • 1Department of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA; Graduate School, Loyola University Chicago, Chicago, IL, USA; Cardiovascular Research Institute, Loyola University Chicago, Maywood, IL 60153, USA.

Cell Reports
|October 20, 2026
PubMed

Keywords:
CP: cell biologyER stressMERCsMIPC2PERKcalcium leakcardiomyocytes

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