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Updated: Oct 22, 2026

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages

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CHK1 phosphorylates TRIM28 at Ser473 to drive NLRP3 inflammasome assembly and inflammatory responses

Peng-Peng Zhu1, Xing-Xing Chen2, Xia-Ying Chen1

  • 1Nanhu Laboratory, Jiaxing, 314000, China.

Biochemical and Biophysical Research Communications
|October 20, 2026
PubMed

Keywords:
CHK1InflammationNLRP3 inflammasomePhosphorylationSUMOylationTRIM28

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