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Updated: Oct 22, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
Current Trends in Hemostatic Agents for Dental and Oral Surgical Procedures: A Narrative Review
Hyun Je Kim1, Kimin Jung2, Dongwook Yang3
1Clinical Assistant Professor, Department of Oral and Maxillofacial Surgery, Incheon St. Mary's Hospital, Incheon, Republic of Korea.
Purpose:
Bleeding is a common concern in dental, oral, and maxillofacial surgery, particularly in patients with increased bleeding risk. This narrative review summarizes current evidence on local and systemic hemostatic agents, including their mechanisms, clinical applications, efficacy, and safety.
Methods:
Literature published from January 2020 through November 2025 was reviewed using predefined search terms related to hemostatic agents and surgical bleeding. Clinical studies, systematic reviews, meta-analyses, narrative reviews, guidelines, and consensus statements were considered. Seven clinical cases were also reviewed to demonstrate practical applications of selected hemostatic agents.
Results:
Mechanical agents provided effective control of routine bleeding, whereas active and flowable agents were useful for persistent or diffuse bleeding. Fibrin-based and combination approaches provided additional support in complex procedures. Tranexamic acid was particularly useful in patients receiving antithrombotic therapy.
Conclusion:
Optimal hemostasis requires a tailored, procedure-specific strategy based on bleeding characteristics, surgical complexity, and patient-specific risk factors.
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