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Danish translation and linguistic validation of the Melanoma Concerns Questionnaire
Julie Renata Bjerremand1, Lisbet Rosenkrantz Hölmich2,3, Amalie Viedemann Mosen2
1Copenhagen Academy of Medical Education and Simulation, Copenhagen University Hospital.
Introduction:
Increased focus on monitoring health-related quality of life (HRQoL) in melanoma patients has highlighted the need for validated instruments such as patient-reported outcome measures (PROMs). Rather than developing new measures, it is generally recommended to translate and linguistically validate a suitable existing PROM.
Methods:
The Melanoma Concerns Questionnaire (MCQ-28) was adapted from English to Danish following the guidelines by the International Society for Pharmacoeconomics and Outcomes Research (ISPOR). A forward-and-backwards translation was conducted, followed by cognitive debriefing interviews based on the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN), focusing on comprehensiveness, comprehensibility and relevance.
Results:
The Danish MCQ-28 was tested on 21 patients, including seven in each risk group. Overall responses were positive, though several patients - especially those at a low risk or further in follow-up process - struggled with the timeframe of certain items. The interviews also revealed that some items were interpreted differently depending on individual patient perspectives.
Conclusions:
By following the ISPOR guideline, a culturally relevant, linguistically validated Danish version of the MCQ-28 was developed. It is a candidate for implementation in Danish melanoma follow-up and for use in international HRQoL research on melanoma patients; however, psychometric validation in a Danish context is necessary.
Funding:
The Herlev and Gentofte Hospital Research Fund.
Trial Registration:
Not relevant.
