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Exploring structure-based drug discovery of GPCRs beyond the orthosteric binding site

Zhao Chen1,2, Xintong Ren2,3, Yu Zhou2

  • 1Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China.

Hlife
|October 22, 2026
PubMed

Keywords:
G-protein coupled receptor (GPCR)allosteric pocketartificial intelligence (AI)negative allosteric modulator (NAM)positive allosteric modulator (PAM)structure-based virtual screening (SBVS)

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