Related Experiment Video
Updated: Oct 24, 2026

08:07
Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
Published on: September 6, 2017
The Novel HLA-DRB4*01:03:49 Allele Was Identified by Next-Generation Sequencing
Yizhen He1, Lina Dong1, Nanying Chen1
1HLA Typing Laboratory, Blood Center of Zhejiang Province, Hangzhou, China.
HLA
|October 22, 2026
Abstract:
HLA-DRB4*01:03:49 differs from HLA-DRB4*01:03:02:01 by one single nucleotide substitution at position 64 C>T.
More Related Videos
Related Concept Videos
Next-generation Sequencing
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Modern Molecular Taxonomy
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

