Related Experiment Video

Updated: Oct 25, 2026

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
00:06

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

OLFM4 promotes intrahepatic cholangiocarcinoma progression through a PKM2-glycolysis-histone lactylation feedback

Shuochen Liu1, Kai Cao1, Changan Chen1

  • 1Department of Hepatobiliary Surgery, The First Affiliated Hospital with Nanjing Medical University; Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences; NHC Key Laboratory of Living Donor Liver Transplantation, Nanjing Medical University, Nanjing, Jiangsu Province, China.

International Journal of Biological Sciences
|October 23, 2026
PubMed

Keywords:
OLFM4PKM2glycolysishistone lactylationintrahepatic cholangiocarcinoma

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