Related Experiment Video
Updated: Oct 25, 2026

Procedures for In Vitro Cultivation of Treponema pallidum, the Syphilis Spirochete
Published on: January 24, 2025
Health vulnerability to vertical transmission of syphilis: validity of constitutive and operational definitions
Maria Júlia Alexandrino Oliveira1, Maria Adelane Monteiro da Silva2, Alice Batista Rodrigues2
1Universidade Federal do Ceará. Sobral, Ceará, Brazil.
Objective:
to develop and analyze the validity evidence of the constitutive and operational definitions of health vulnerability for pregnant women in relation to vertical transmission of syphilis.
Methods:
a psychometric study, based on the Health Vulnerability Model, protocols from the Ministry of Health, updating the scoping review and conducting a concept analysis. Content validity evidence was analyzed by ten judges. The Content Validity Ratio was used to select operational definitions with a score equal to or greater than 0.8.
Results:
the dimensions were divided into nine subdimensions with 17 subconcepts, highlighting "health-disease situation", "knowledge", "attitude", "self-care", "lifestyle", "cultural differences", "social support", "situations of sexual, physical, verbal, and psychological violence", "discrimination", and "general gender inequalities".
Final Considerations:
the definitions obtained good validity evidence indices. Thirty operational definitions were developed for construct assessment.
Related Concept Videos
Genital Herpes
Transmission of Pathogens
Sexually Transmitted Infections
Amebiasis
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Principles of Disease Surveillance
