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MCT6 is an intestinal Lac-Phe exporter required for metformin-associated weight loss

Shuke Xiao1, Alan Sheng-Hwa Tung2, Jan Spaas3

  • 1Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA; Wu Tsai Human Performance Alliance, Stanford University, Stanford, CA 94305, USA.

Cell
|October 23, 2026
PubMed

Keywords:
Lac-PheMCT6SLC16A5circulatinglactatemetabolitesmetforminobesitytransporterweight loss

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