Related Experiment Video

Updated: Oct 25, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

Exploring a Druggable Hydrophobic Tunnel in the 5-HT2A Receptor with Potent Phenethylamines

Icaro A Simon1, Eline Pottie2, Madeleine K Jensen1

  • 1Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Jagtvej 160, 2100Copenhagen, Denmark.

Journal of Medicinal Chemistry
|October 23, 2026
PubMed

Keywords:
5-HT2ARhydrophobic tunnelphenethylamineserotonergic psychedelicsstructure-guided drug design

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