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Published on: May 16, 2013
Severe Plasmodium falciparum infection with multi-organ involvement in an asplenic patient: a case report
Bolette Wittenberg1, Gitte Nyvang Hartmeyer2, David Fuglsang-Damgaard3
1Department of Clinical Microbiology, Odense University Hospital, J. B. Winsloews Vej 4, 5000, Odense C, Denmark. bolette.wittenberg@rsyd.dk.
Abstract:
Plasmodium falciparum is the leading cause of severe malaria. The spleen plays a central role in the clearance of the infection in conjunction with antimalarial treatment. Splenectomized patients lack sufficient clearance functions. We report a case of severe P. falciparum infection with multi-organ involvement acquired in Uganda in a splenectomized patient with a persistently high parasitemia level despite appropriate antimalarial treatment. The case emphasizes the challenges associated with severe malaria in asplenic patients.
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