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Updated: Oct 26, 2026

Cerebellar Regional Dissection for Molecular Analysis
Published on: December 5, 2020
Atypical Cerebellar Vermis Signal Abnormality in Wernicke Encephalopathy
Tanya F Panwala1, Yu Sakai2, J Eric Schmitt2
1Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Abstract:
Wernicke encephalopathy is classically associated with signal changes involving the mamillary bodies, medial thalami, and periaqueductal gray matter on MRI. We present a case of a 57-year-old woman with progressive Wernicke encephalopathy with imaging abnormalities in the cerebellar vermis and bilateral cerebellar hemispheres. This case highlights atypical imaging features that can be seen in Wernicke encephalopathy and emphasizes the importance of early clinical recognition to prevent progression.
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