Pleomorphic Adenoma of the Palate: A Case Report

Pleomorphic adenoma is a benign mixed salivary gland neoplasm that most commonly arises in the parotid gland, while involvement of the minor salivary glands is uncommon. This case report describes a 46-year-old woman who presented with a painless, gradually enlarging swelling on the right posterolateral aspect of the palate for one year. Intraoral examination revealed a solitary, firm, immobile, non-tender, non-pulsatile swelling measuring approximately 3 × 2 cm, covered by smooth and intact mucosa. Histopathological examination of an incisional biopsy demonstrated epithelial proliferation arranged in sheets, nests, cords, and duct-like structures, together with plasmacytoid cells and hyalinized, myxoid, and chondroid-like stromal areas, confirming pleomorphic adenoma. The lesion was completely excised under local anesthesia along with the associated mucoperiosteum and eroded palatal bone, and the wound was closed with 3-0 silk sutures. The patient experienced no immediate postoperative complications and showed no clinical recurrence during six months of follow-up. This case emphasizes the importance of histopathological confirmation, complete surgical excision, and continued postoperative surveillance in the management of pleomorphic adenoma of the hard palate.