Orbital Calcifying Fibrous Tumor: A Case Report

Calcifying fibrous tumors (CFTs) are uncommon benign soft-tissue tumors characterized by dense hyalinized collagen, spindle-shaped cells, and calcifications and can occur in various organs throughout the body. We present a detailed case report of an orbital CFT in a young Saudi girl.

Our patient was a 12-year-old girl who presented with right-eye proptosis that began at the age of 5 years and remained stable thereafter. Initial computed tomography revealed a mass but could not precisely determine its location or establish a specific diagnosis. A complementary magnetic resonance imaging study was recommended and suggested a possible lymphoproliferative or inflammatory process. Subsequent biopsy revealed a fibrous lesion consistent with a CFT due to the presence of microcalcifications. A course of oral corticosteroids was initiated to reduce the proptosis; however, no clinical improvement was observed.

CFTs were first described in 1988 and recognized by the World Health Organization (WHO) in 2002. Most cases are asymptomatic; however, they may present as painless masses, as demonstrated in this case of orbital proptosis. Diagnosis varies according to the site of involvement, with imaging and histopathological findings playing key roles. Surgical resection remains the treatment of choice and is associated with an excellent prognosis and low recurrence rates. This case underscores the importance of increasing awareness of CFTs among healthcare professionals, particularly when they occur in atypical locations such as the orbit.