Related Experiment Video
Updated: Oct 26, 2026

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Impact of newly diagnosed multiple sclerosis on marital status and partner relationship
Enriqueta Vallejo-Yagüe1, Lisa Sanak2, Nina Steinemann3
1Swiss Multiple Sclerosis Registry (SMSR), Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
Introduction:
Evidence on short-term impact of multiple sclerosis (MS) diagnosis on intimate relationships remains limited. This study investigated the perceived impact of MS diagnosis on relationship status within the first year following diagnosis.
Methods:
This survey-based observational study used data from the Swiss Multiple Sclerosis Registry (SMSR). Factors potentially associated with perceived MS direct impact on relationship status within the first year after diagnosis were explored using logistic regression. Among participants reporting that MS impacted their relationship, we explored changes in relationship status and factors associated with relationship dissolution.
Results:
Among 881 participants included (74% female), 453 were married, 235 with a partner, and 193 single at diagnosis. Overall, 89 participants (10.1%) reported that MS diagnosis impacted their relationship (i.e., 6.2% of married; 14.5% of partnered; 14% of single). Compared with married participants, partnered (ORadj 2.3; 95%CI 1.30-4.06) and single participants (ORadj 2.26; 95%CI 1.25-4.07) were more likely to report impact. Cognitive symptoms were associated with higher odds of reporting impact (ORadj 2.02, 95%CI 1.28-3.19). Among married participants, primary progressive MS was associated with increased odds of relationship impact (ORadj 3.21; 95%CI 1.15-8.33). Among partnered participants, men were more likely than women to report an impacted relationship (ORadj 3.00; 95%CI 1.23-7.25). Among participants with reported relationship impact, relationship trajectories included continuation, strengthening, and dissolution. None of the studied factors were associated with relationship dissolution.
Conclusion:
One in ten participants reported MS diagnosis impacting their relationship, and consequent relationship changes were heterogeneous, suggesting that this influence may belong to broader psychosocial processes.
Related Concept Videos
Multiple Sclerosis l: Introduction
Social Relationships and Well-Being
Ending Relationships
Close Relationships and Culture
Couples Therapy
Core Principles and Techniques
Couples therapy often incorporates cognitive-behavioral principles to identify and modify negative...
Relationship Formation
