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Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
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Structure-guided development of G protein-biased apelin receptor agonists for cardiovascular disease

Weiwei Wang1,2, Jiangrong Zhang1, Jiahua Zhang1

  • 1Department of Pathology and Department of Pharmacology of Sir Run Run Shaw Hospital, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, and Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou 310058, China.

Journal of Zhejiang University. Science. B
|October 25, 2026
PubMed

Keywords:
Apelin receptor (APLNR)Biased signalingDrug designG protein-coupled receptor

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