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Cynomolgus Monkey (Macaca fascicularis) Embryo Models: From Developmental Benchmarks to Functionally Testable
Yeojeong Jeong1,2, Jongwon Byun2,3, Sung-Hwan Moon1
1Department of Animal Science and Technology, Chung-Ang University, Anseong, Republic of Korea.
Journal of Medical Primatology
|October 26, 2026
Abstract:
Stem cell-based embryo models now reconstruct increasingly advanced stages of mammalian development, but developmental fidelity remains a central limitation. This review examines why cynomolgus monkey systems are biologically necessary, how natural embryos and emerging technologies benchmark primate development, and how advanced monkey embryoids can strengthen interpretation of human embryo models.
