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An Inverse Design Workflow for Solvent Mixtures Based on Hansen Solubility Parameters

Xue Fang1,2, Shaohua Li1,3, Bo Gao4

  • 1School of Chemistry, University of Bristol, Cantock's Close, BristolBS8 1TS, U.K.

Journal of Chemical Information and Modeling
|October 26, 2026
PubMed

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A solution is a homogeneous mixture composed of a solvent, the major component, and a solute, the minor component. The physical state of a solution—solid, liquid, or gas—is typically the same as that of the solvent. Solute concentrations are often described with qualitative terms such as dilute (of relatively low concentration) and concentrated (of relatively high concentration).
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