Injecting Artificial Intelligence into Medicine

Introducing a new journal from NEJM Group: NEJM AI, a platform aimed at informing readers and guiding the responsible development of artificial intelligence (AI) to enhance the quality of health care. This editorial reflects on AI's historical milestones and current capabilities, particularly large language models, and the imperative for their rigorous clinical evaluation. It discusses the crucial need for AI in medicine to undergo the same level of scrutiny as any clinical intervention, predominantly through randomized controlled trials, despite the challenges posed by the technology's complexity. Looking forward, NEJM AI commits to fostering a multidisciplinary discourse and the development of a transparent, patient-centered approach to AI in health care, with an emphasis on the critical importance of diverse and accessible datasets. The editorial concludes by envisioning a future where NEJM AI not only informs but actively shapes the ethical integration of AI into a health care system that respects patient autonomy and upholds the highest standards of care.