Related Experiment Video
Updated: Oct 27, 2026

Line Shape Analysis of Dynamic NMR Spectra for Characterizing Coordination Sphere Rearrangements at a Chiral Rhenium Polyhydride Complex
Published on: July 27, 2022
Diastereoselective Axial-to-Chelate-Puckering Chirality Transfer in cis-[PtCl2(DABN)] Complexes
Andrea Maluenda1, Tamara Bolaño2, Pablo J Sanz Miguel1
1Departamento de Química Inorgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), Universidad de Zaragoza-CSIC, 50009Zaragoza, Spain.
Abstract:
Axially chiral 1,1'-binaphthalene-2,2'-diamine (DABN) was used to control chelate-ring puckering in cis-[PtCl2(DABN)] complexes. Coordination of Ra- or Sa-DABN affords the enantiomeric complexes cis-λ-[PtCl2(Ra-DABN)] (λ,Ra-1) and cis-δ-[PtCl2(Sa-DABN)] (δ,Sa-1), respectively, with no evidence for mismatched diastereomers. X-ray crystallography shows that axial ligand chirality is translated into a configurationally locked λ or δ pucker of the seven-membered metallacycle. NMR spectroscopy supports retention of the structure in CD3CN, whereas kinetic studies in DMSO-d6 reveal pseudo-first-order DABN displacement by solvent. The enantiomeric complexes display intense mirror-image CD spectra, highlighting DABN as an effective axial chirality source for axial-to-chelate-puckering chirality transfer.
More Related Videos
11:44Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-(phosphinetriyl)tripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
06:35Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
Published on: February 15, 2016
Related Concept Videos
Prochirality
Stereoisomerism
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
Chirality at Nitrogen, Phosphorus, and Sulfur
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Stereoisomerism of Cyclic Compounds
Complexation Equilibria: The Chelate Effect