Related Experiment Video
Updated: Oct 28, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Why Medicine Must Become a Knowledge-Processing Discipline
Isaac S Kohane1,2, Andrew L Beam1,2,3, Arjun K Manrai1,2
1Department of Biomedical Informatics, Harvard Medical School, Boston.
Abstract:
AbstractThis Perspective summarizes the episode of NEJM AI Grand Rounds where Drs. Andrew Beam and Arjun Manrai hosted Dr. Isaac Kohane.1 Dr. Kohane shares his career journey and reflects on the progress of AI in medicine over the past several decades. We also discuss the importance of multidisciplinary training in AI and medicine and the motivation behind the founding of NEJM AI and the Department of Biomedical Informatics at Harvard Medical School.
Related Concept Videos
Methods of Documentation II: POMR
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Biopharmaceutics and Pharmacokinetics: Overview
Critical Thinking II
Methods of Documentation VI: Case Management Model
For example, a patient with a chronic illness...
Therapeutic Drug Monitoring: Overview and Classification
