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Comparative Analysis of Inflammatory Responses in Pediatric and Adult Cases of Peritonsillar Abscess: A Retrospective
1Department of Otorhinolaryngology, Bursa City Training and Research Hospital, Bursa, Turkey.
Objective:
Peritonsillar abscess (PTA) is a common deep neck infection affecting both children and adults. In this retrospective study, we aimed to evaluate and compare the diagnostic and therapeutic approaches as well as the role of inflammatory markers in predicting hospitalization duration among different age groups with PTA.
Methods:
A total of 162 patients (26 pediatric, 136 adults) treated for PTA between January 2022 and May 2025 were analyzed. Patients were grouped by age (≤10, 10-17, ≥18 years) and by length of hospital stay (≤3 days, >3 days). Hematologic and inflammatory markers, including neutrophil (N), lymphocyte (L), monocyte (M), thrombocyte (T), C-reactive protein (CRP), N/L ratio (NLR), CRP/L ratio (CLR), systemic immune-inflammation index (SII), and systemic inflammatory response index (SIRI) were compared statistically.
Results:
Incision drainage or needle aspiration was performed in all. No significant differences were found among age groups in laterality, drainage type, CRP, CLR, NLR, SII, or SIRI. Female predominance was noted in children. Pediatric patients had significantly higher N, L, and T counts and longer hospitalization compared with adults. The most common antibiotic regimens were cefotaxime + clindamycin in children and ampicillin/sulbactam + metronidazole in adults; culture sampling rates were 80.7% and 24.2%, respectively. Streptococcus pyogenes was the most frequently isolated pathogen in all age groups.
Conclusion:
An analysis of prolonged hospitalizations across all age groups revealed that only the N count and SII were significant predictors of longer hospital stays, highlighting their potential as prognostic indicators.
