Related Experiment Video
Updated: Oct 28, 2026

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
Estimation of Genomic Breeding Values for Economic Traits in Alxa-Type Cashmere Goats Using Bayesian Methods
Jie Quan1, Tiecheng Wu1,2, Tao Wang1
1Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot 010031, China.
Abstract:
Conventional breeding has a long generation interval; genomic selection can enable early selection and shorten the breeding process in cashmere goats. This study aimed to estimate genomic breeding values for economic traits in Inner Mongolia (Alxa-type) cashmere goats using Bayesian methods. Whole-genome resequencing at 1× depth was performed on 491 Alxa-type cashmere goats (40 males and 451 females), and genotypes were imputed to 10× using a reference panel with an average imputation accuracy of 97.90%. Fixed effects were determined by analysis of variance, and breeding values for body weight, cashmere fiber diameter, and cashmere yield were estimated using Bayes A, Bayes B, and Bayes C; prediction accuracy and unbiasedness were evaluated by five-fold cross-validation. Measurement year and group affected all three traits highly significantly (p < 0.01); sex affected body weight and cashmere yield highly significantly (p < 0.01) but no significant effect on cashmere fiber diameter (p > 0.05); and maternal age had a significant effect on body weight (p < 0.05), but no significant effect on cashmere fiber diameter or cashmere yield (p > 0.05); group had a highly significant effect on all three traits (p < 0.01). Breeding values were estimated using Bayes A, Bayes B, and Bayes C, with five-fold cross-validation, and the three methods performed comparably overall in this population.
Related Concept Videos
Multiple Allele Traits
Pedigree Analysis
Monohybrid Crosses
Hardy-Weinberg Principle
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Estimating Population Standard Deviation
