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Published on: February 11, 2014
Short- and Long-Term Outcomes After MAIA-Guided Biofeedback Training in 346 Patients with Low Vision: A Retrospective
Mariana A M Misawa1, Aljeena Rahat Qureshi1, Ghaliah Nsour1
1Department of Ophthalmology and Vision Sciences, Toronto Western Hospital, University Health Network, 399 Bathurst St., Toronto, ON M5T 2S8, Canada.
Purpose:
To describe short- and long-term visual outcomes after MAIA microperimetry biofeedback training (BT) in a low-vision rehabilitation cohort.
Methods:
Retrospective study of patients who completed BT between 2017 and 2023 (4.1 ± 0.6 sessions). The MAIA device recorded P1 and P2 parameters, defined as the percentage of fundus-tracked fixation points falling within device-defined circular windows centered on the trained retinal locus (TRL).
Outcomes:
baseline, short-term follow-up (<6 months), and long-term follow-up (≥6 months): P1, P2, best-corrected distance visual acuity (BCVA), near visual acuity, fixation stability (BCEA), mean retinal sensitivity (dB), and reading speed (wpm) MNRead app.
Results:
A total of 346 participants were included. Median P1 increased from 21.5% at Session 1 to 32.0% at Session 5, and P2 increased from 66.0% to 81.5%. Distance and near visual acuity improved significantly at short-term follow-up but were not significantly different from baseline in the overall cohort at long-term follow-up. Reading speed, BCEA, and mean retinal sensitivity did not show significant longitudinal changes. In an exploratory secondary analysis excluding eyes with worsening BCVA, distance and near visual acuity remained significantly improved at long-term follow-up.
Conclusions:
MAIA-guided BT was associated with improved within-training fixation performance and short-term visual acuity in this heterogeneous retrospective cohort. Long-term improvement was not demonstrated in the overall cohort; exploratory analyses suggest that underlying disease progression may influence long-term outcomes. Prospective controlled studies are required to determine durability and efficacy.
