Related Experiment Video
Updated: Oct 28, 2026

Adapting Taylor Dispersion to Measure the Dispersion Coefficient of Electrolyte Solutions via an Accessible Microfluidic Setup
Published on: October 7, 2025
Unlocking the Full Potential of Taylor Dispersion Analysis Through Advanced Detection
1Institut des Sciences Analytiques, CNRS, Université Claude Bernard Lyon 1, Université de Lyon, UMR 5280, 69100 Villeurbanne, France.
Abstract:
Today, pharmaceutical sciences rely on a wide range of innovative therapeutics of varying sizes: nanoparticles, proteins, antibodies, and nanocarriers for drug delivery. Measuring their size is one of the crucial parameters in their characterization, to ensure drug safety, stability, and effectiveness. Over the past two decades, Taylor Dispersion Analysis has emerged as an important sizing method. Its scope of application is perfectly suited to the sizes of these therapeutics. By design, it can be coupled with a wide range of detectors, and extensive research has been conducted in this field. In this review, we will present an overview of the studies conducted, and discuss how the application drives the choice of one detector or another (size measurement, aggregation studies, interaction studies, and other analyses, performed in both simple biological buffers and in more complex media, particularly serum) and makes Taylor Dispersion Analysis a highly versatile tool.
Related Concept Videos
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
Tandem Mass Spectrometry
Discrete Fourier Transform
Discrete-Time Fourier Series
For a discrete-time periodic signal x[n]...
¹H NMR: Interpreting Distorted and Overlapping Signals
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...

