Don't discard the supernatant: pleural fluid cfDNA for molecular profiling in lung cancer
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Updated: Oct 31, 2026

06:53
Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids
Published on: June 8, 2019
1Pleural Medicine and Ultrasound-Guided Intervention Unit, Department of Internal Medicine, Arnau de Vilanova University Hospital, Lleida, Spain josemporcel@icloud.com.
The European Respiratory Journal
|October 29, 2026
Abstract:
Pleural fluid supernatant cfDNA should be routinely preserved and can already be used selectively for molecular profiling in NSCLC, while broader implementation requires prospective clinical validation.

