Integrated Global Strategies for Toxoplasmosis Control Under the One Health Framework
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Updated: Oct 31, 2026

QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
Published on: June 22, 2017
Yetian Li1, Wuerguli Alimu1, Kaiyu Xu1
1Ningbo University School of Medicine, Ningbo University, Ningbo, China, nbu.edu.cn.
Abstract:
Toxoplasma gondii is a globally distributed zoonotic parasite that infects approximately one-third of the human population. Its intricate life cycle involving multiple hosts, combined with the remarkable environmental resilience of oocysts, renders it one of the most difficult pathogens to control. Toxoplasmosis imposes substantial public health and economic burdens, encompassing congenital infections, opportunistic diseases among immunocompromised individuals, reproductive losses in livestock, and persistent environmental contamination that perpetuates transmission. Conventional single-sector interventions addressing human, animal, or environmental health in isolation have proven inadequate for sustainable control. The One Health framework offers an integrative approach that connects human, animal, and environmental health through cross-sectoral collaboration, technological innovation, and community engagement. This review summarizes the epidemiological features and major transmission routes of T. gondii, and proposes comprehensive prevention and control strategies grounded in the One Health paradigm. Implementing this framework can bridge disciplinary boundaries, enhance early surveillance, and establish a robust, long-term system to mitigate T. gondii transmission, thereby protecting human, animal, and ecosystem health.
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