Bone collagen improves bone regeneration after jaw cyst enucleation: a prospective nonrandomized controlled study
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Ke Ma1, Zhenxing Liu2, Luyang He1
1School of Stomatology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China; School of Stomatology, Shandong First Medical University, Jinan, Shandong, China.
Objective:
This study evaluated the clinical effectiveness of bone collagen for reconstruction of bone defects after jaw cyst surgery.
Methods:
Fifty patients with jaw cysts were enrolled and assigned to a study group receiving bone collagen implantation or a control group receiving absorbable gelatin sponge. All patients underwent cyst enucleation, followed by adjunctive biomaterial placement according to group allocation. Bone regeneration was assessed using cone-beam computed tomography at 3 and 6 months postoperatively. Defect volume reduction and bone density were quantitatively evaluated.
Results:
Baseline characteristics and perioperative outcomes did not differ significantly between the two groups. At 3 and 6 months postoperatively, bone density was higher in the study group than in the control group. Cyst volume reduction was also greater in the study group. Postoperative complications occurred more frequently in the control group. Imaging analysis showed earlier and more complete bone regeneration in the bone collagen group.
Conclusions:
After jaw cyst enucleation, collagen placement was associated with improved bone density recovery, faster reduction of the residual cavity, and a lower rate of early postoperative complications. These findings suggest that collagen may be a useful adjunctive material for supporting bone healing in jaw defects.
