Electrochemically Driven Phenazine Autoxidation Coupled With Supported Liquid Membrane Technology for Hydrogen Peroxide Production

Electrosynthesis offers a direct route to utilize clean electricity to create low-emission pathways for chemical manufacturing. For direct electrosynthesis of highly active compounds such as hydrogen peroxide (H₂O₂), however, the close coupling of product formation and decomposition at electrode interfaces, together with energy intensive product-electrolyte separation, leads to energy losses and limited scalability. Here, we develop an electrified supported liquid membrane platform as a scalable and practical method for H₂O₂ production as an important model compound. In this architecture, electrons from an external power source are temporarily stored in a designed organic mediator that is subsequently autoxidized within a physically segregated supported liquid membrane domain. This structural-decoupling strategy suppresses electrode driven decomposition, simplifies product handling, and permits independent tuning of electrochemical, transport, and product formation environments within a compact, modular device constructed from inexpensive components. The platform produces high-purity aqueous H₂O₂ with Faradaic efficiencies up to 80%. We further demonstrate direct, on-site utilization of the generated oxidizing equivalents via in situ Fenton oxidation of an organic contaminant, thereby converting intermittent renewable electricity into localized water-treatment capability. More broadly, this strategy establishes an integrated and flexible reactor design framework for multiphase, electrochemically mediated synthetic processes beyond H₂O₂.