Cell death in context: From mechanisms to interventions
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Updated: Nov 2, 2026

Quantification of Cytokine-Induced Cell Death in Human Colonic Organoids Using Live Fluorescence Microscopy
Published on: August 2, 2024
Abstract:
When, how, and why cells die, and what happens when they survive, have profound consequences for development, immunity, and disease. To coincide with the Cell Press Symposium "Taking programmed cell death from mechanisms to interventions," we bring together perspectives from researchers across career stages and areas of cell death research. From emerging mechanisms and consequences of cell death to opportunities for therapeutic intervention, these voices highlight a rapidly evolving field and the questions that will shape its future.
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Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the 20th century...
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