Aspimultiol A, a new spirostane-type steroid from Aspidistra multiflora
Diep Xuan Ky Nguyen1,2, Thanh Hoa Vo3,4, Dinh Tri Mai1,2
1Institute of Advanced Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam.
Abstract:
For the first time, a phytochemical investigation of the leaves and rhizomes from Aspidistra multiflora was studied. One new spirostane-type steroid, commonly named aspimultiol A (1), along with four other analogues (2-5) were separated using various chromatographic methods. For the first time, all compounds except 3 were clarified from the Aspidistra genus, and all of them were testified from this species. Their structures were illuminated via comprehensive and extensive HRMS, IR, and NMR spectral recognition. The affects on HeLa and MCF-7 cancer cells of purified metabolites (1-3) were measured via SRB assay.
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