[Clinical and infectious disease perspective, rationale for pneumococcal vaccination in the elderly]
1Infectiologue, service des maladies infectieuses, centre hospitalier Annecy Genevois, Pringy, France.
Abstract:
Pneumococcus (Streptococcus pneumoniae) remains a major cause of morbidity and mortality among the elderly. The often-atypical clinical presentation, the prevalence of comorbidities, and immunosenescence all contribute to the severity of infections. Despite the impact of conjugate vaccines, epidemiological trends, marked by serotype replacement, warrant an adaptation of vaccination strategies. New-generation vaccines, notably PCV20 and PCV21, are part of this trend.
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