Case Report: Selective PRP application during staged MEEK-based reconstruction of extensive deep burns

Staged grafting may be required after extensive deep burns when donor skin is limited. We describe the clinical course of three patients treated with selective platelet-rich plasma (PRP) application during MEEK-based reconstruction.

Three men with 21%, 45%, and 40% total body surface area (TBSA) burns underwent staged debridement and autologous grafting. PRP was administered during two of two, three of four, and one of three burn-wound operations, respectively. Approximate, chart-recorded graft-take estimates ranged from 80% to 95% across procedures, including procedures without PRP; these estimates were not obtained using a documented standardized measurement method. At discharge, Patient 1 had complete epithelialization, whereas Patients 2 and 3 had small residual wounds. At photographic follow-up approximately 2.5-3.5 months after discharge, no recurrent deep burn wounds or clinically documented infection were noted; Patient 1 had superficial scar ulcerations. Retrospectively reported Vancouver Scar Scale (VSS) scores were 8, 9, and 10, with incomplete documentation of the original assessment method.

The cases describe an individualized staged-reconstruction pathway incorporating selectively applied PRP. They do not establish a separate effect of PRP on graft take, infection, healing, or scar outcomes.