Exercise trains the liver to save the heart
Related Experiment Video
Updated: Nov 8, 2026

Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System
Published on: May 12, 2023
Brian N Finck1, Rita T Brookheart2
1Center for Human Nutrition, Department of Medicine, Division of Nutritional Science and Obesity Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Abstract:
Wang and colleagues1 demonstrate that exercise triggers the liver to release clusterin into the bloodstream, improving cardiac remodeling and myocyte proliferation post-myocardial infarction. Their findings add another mechanistic facet to the complexity and controversial role of clusterin in cardiac injury.
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